Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 3/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | AHCY | P23526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664192 | 0.79 | USP7 (0.34) | KDM5AKDM5BNAPRTPRKCIUSP7 | |
| SCHEMBL26471836 | 0.75 | USP7 (0.35) | PRKCIUSP7 | |
| SCHEMBL29187785 | 0.72 | CYP19A1 (0.33) | PRKCIUSP7RET | |
| SCHEMBL28645007 | 0.71 | KDM5A (0.35) | KDM5AKDM5B | |
| SCHEMBL23901911 | 0.68 | USP7 (0.35) | PRKCIUSP7 | |
| SCHEMBL22493647 | 0.68 | USP7 (0.35) | PRKCIUSP7RET | |
| SCHEMBL26686534 | 0.68 | USP7 (0.35) | PRKCIUSP7 | |
| SCHEMBL28907422 | 0.68 | NOS3 (0.37) | PRKCIUSP7 | |
| SCHEMBL30439509 | 0.67 | PRKCQ (0.43) | NAPRT | |
| Potassium Ion SCHEMBL28907435 | 0.67 | USP7 (0.34) | PRKCIUSP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052866-A | Crystal form of free base of nitrogen-containing heteroaromatic derivative | 上海翰森生物医药科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113493440-A | Salt of nitrogen-containing heteroaromatic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-111295374-A | Aza-containing aromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2020-06-16 | — | — | CN | disclosed |