Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 4/20 | 0.33 |
| ▸ | NOS2 | P35228 | 4/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907422 | 0.76 | NOS3 (0.37) | USP7NOS3NOS2NOS1F12 | |
| SCHEMBL22493647 | 0.76 | USP7 (0.35) | USP7NOS3NOS2NOS1F12 | |
| SCHEMBL26471836 | 0.76 | USP7 (0.35) | USP7NOS3NOS2NOS1F12 | |
| SCHEMBL26686534 | 0.76 | USP7 (0.35) | USP7NOS3NOS2NOS1F12 | |
| Potassium Ion SCHEMBL28907435 | 0.74 | USP7 (0.34) | USP7NOS3NOS2NOS1F12 | |
| SCHEMBL3388421 | 0.72 | NOS3 (0.37) | USP7NOS3NOS2NOS1F12 | |
| SCHEMBL12540026 | 0.72 | ESR2 (0.35) | USP7NOS3NOS2NOS1 | |
| SCHEMBL12540028 | 0.72 | ESR2 (0.35) | USP7NOS3NOS2NOS1 | |
| SCHEMBL28284231 | 0.72 | TDO2 (0.40) | USP7NOS3NOS2NOS1 | |
| SCHEMBL28664192 | 0.69 | USP7 (0.34) | USP7PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021197452-A1 | CRYSTAL FORM OF FREE ALKALI OF NITROGEN-CONTAINING AROMATIC DERIVATIVES | 上海翰森生物医药科技有限公司 | 2021-10-07 | — | — | WO | disclosed |