Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664194 | 0.79 | KDM5A (0.35) | USP7KDM5AKDM5BNAPRTPRKCI | |
| SCHEMBL28645004 | 0.70 | KDM5A (0.33) | KDM5AKDM5B | |
| SCHEMBL28907422 | 0.69 | NOS3 (0.37) | USP7PRKCI | |
| SCHEMBL26471836 | 0.69 | USP7 (0.35) | USP7PRKCI | |
| SCHEMBL26686534 | 0.69 | USP7 (0.35) | USP7PRKCI | |
| SCHEMBL23901911 | 0.69 | USP7 (0.35) | USP7PRKCI | |
| SCHEMBL22493647 | 0.69 | USP7 (0.35) | USP7PRKCI | |
| Potassium Ion SCHEMBL28907435 | 0.68 | USP7 (0.34) | USP7PRKCI | |
| SCHEMBL28915965 | 0.67 | USP7 (0.38) | USP7 | |
| SCHEMBL3388421 | 0.66 | NOS3 (0.37) | USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052866-A | Crystal form of free base of nitrogen-containing heteroaromatic derivative | 上海翰森生物医药科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113493440-A | Salt of nitrogen-containing heteroaromatic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-111295374-A | Aza-containing aromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2020-06-16 | — | — | CN | disclosed |