Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | NEK2 | P51955 | 1/20 | 0.51 |
| ▸ | MAPK15 | Q8TD08 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 3/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | MELK | Q14680 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279957 | 0.84 | PRKD1 (0.67) | FYNMAPTPRKD1SMN1; SMN2NPC1 | |
| SCHEMBL25438397 | 0.83 | PRKD1 (0.69) | FYNMAPTPRKD1SMN1; SMN2NPC1 | |
| SCHEMBL10389970 | 0.82 | MAPT (0.54) | FYNMAPTPRKD1SMN1; SMN2NPC1 | |
| SCHEMBL10357366 | 0.78 | RAB9A (0.65) | MAPTPRKD1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16844434 | 0.77 | PRKD1 (0.56) | FYNMAPTPRKD1SMN1; SMN2NPC1 | |
| SCHEMBL17279945 | 0.76 | PRKD1 (0.64) | MAPTPRKD1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1528519 | 0.76 | FYN (0.55) | FYNMAPTPRKD1SMN1; SMN2NPC1 | |
| SCHEMBL6669387 | 0.74 | MAPT (0.56) | MAPTPRKD1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5612710 | 0.74 | MAPT (0.59) | FYNMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6924233 | 0.74 | SMN1; SMN2 (0.56) | FYNMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |