Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670139 | 0.86 | KMT2A (0.57) | CCR5KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL5318078 | 0.77 | CCR5 (0.52) | CCR5KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL10334300 | 0.76 | TDP1 (0.52) | KMT2AMAPTALDH1A1MEN1HPGD | |
| SCHEMBL10298033 | 0.74 | AR (0.45) | CCR5MAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL15306485 | 0.74 | KMT2A (0.56) | KMT2AMAPTALDH1A1MEN1HPGD | |
| SCHEMBL23117424 | 0.73 | MAPT (0.47) | KMT2AMAPTALDH1A1MEN1HPGD | |
| Methoxymethane SCHEMBL5318080 | 0.72 | CCR5 (0.51) | CCR5KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL24074030 | 0.72 | LMNA (0.49) | KMT2AMAPTALDH1A1MEN1HPGD | |
| SCHEMBL179090 | 0.72 | CCR5 (0.60) | CCR5SMN1; SMN2PKMGAALMNA | |
| SCHEMBL15306484 | 0.72 | MEN1 (0.59) | CCR5KMT2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710242-A | Compositions and methods for treating neurodegenerative disorders | 吉恩特药业株式会社 | 2021-11-26 | — | — | CN | disclosed |