Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664810 | 0.86 | CCR5 (0.55) | KMT2AALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL10298034 | 0.83 | EGFR (0.60) | KMT2AALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL3299225 | 0.78 | CA12 (0.62) | KMT2AALDH1A1MAPTSMN1; SMN2PKM | |
| SCHEMBL15306485 | 0.77 | KMT2A (0.56) | KMT2AALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL23117425 | 0.75 | KCNJ1 (0.47) | KMT2AALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL23117424 | 0.75 | MAPT (0.47) | KMT2AALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL5941247 | 0.74 | KMT2A (0.62) | KMT2AALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL15306483 | 0.74 | ALDH1A1 (0.73) | KMT2AALDH1A1HPGDMAPTLMNA | |
| SCHEMBL10334067 | 0.73 | KMT2A (0.71) | KMT2AALDH1A1MAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL1977674 | 0.73 | KMT2A (0.71) | KMT2AALDH1A1HPGDMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710242-A | Compositions and methods for treating neurodegenerative disorders | 吉恩特药业株式会社 | 2021-11-26 | — | — | CN | disclosed |