Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.50 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654978 | 0.82 | HDAC1 (0.53) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL19633384 | 0.76 | CDK1 (0.50) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL17078412 | 0.72 | HDAC1 (0.51) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL19633358 | 0.71 | CDK1 (0.52) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL6817839 | 0.70 | HDAC1 (0.67) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL28657767 | 0.69 | AMPD1 (0.43) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL28662851 | 0.69 | AMPD1 (0.43) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8348688 | 0.68 | HDAC1 (0.64) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL28655087 | 0.67 | AMPD1 (0.43) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL15756435 | 0.67 | CCNE2 (0.61) | HDAC1HDAC2YTHDC1CDK1CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113645977-A | Compounds, compositions and methods for treatment of disease | F-星治疗公司 | 2021-11-12 | — | — | CN | disclosed |