SCHEMBL28665196

SCHEMBL28665196

O=C(c1ccccc1F)N(CCc1ccccc1)Cc1ccccc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
HTT P42858 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
KDM4E B2RXH2 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
LPAR1 Q92633 1/20 0.47
LPAR5 Q9H1C0 1/20 0.47
KMT2A Q03164 4/20 0.47
RAB9A P51151 4/20 0.47
NPC1 O15118 2/20 0.47
TDP1 Q9NUW8 2/20 0.46
MEN1 O00255 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
GAA P10253 1/20 0.45
POLB P06746 1/20 0.45
GPR52 Q9Y2T5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28669607 0.81 TP53 (0.47) ALDH1A1KDM4ELPAR1LPAR5MAPT
SCHEMBL3456433 0.79 TDP1 (0.70) HTTKDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL707675 0.73 LPAR1 (0.79) LPAR1
SCHEMBL4066112 0.72 TP53 (0.55) ALDH1A1SMN1; SMN2KDM4ELPAR1KMT2A
SCHEMBL15111089 0.71 RCE1 (0.68) LPAR1LPAR5KMT2ARAB9ANPC1
SCHEMBL28671251 0.70 LPAR1 (0.44) ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL12128164 0.69 BCHE (0.53) ALDH1A1KDM4EL3MBTL1
SCHEMBL254969 0.69 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1
SCHEMBL14610603 0.69 L3MBTL1 (0.53) ALDH1A1HTTLPAR1KMT2ARAB9A
SCHEMBL7228409 0.68 MEN1 (0.61) ALDH1A1KMT2ARAB9ANPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651179-B 2- (2-aminobenzoyl) benzoic acid derivatives and process for preparing the same 厦门华厦学院 2021-12-03 CN disclosed