SCHEMBL2866524

SCHEMBL2866524

Cc1ccc(N(OCO)OCO)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
ACHE P22303 3/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
RAB9A P51151 2/20 0.35
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MAPT P10636 3/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.32
AGXT P21549 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80211 0.83 ALDH1A1 (0.39) ALDH1A1TSHRACHECYP2C19TDP1
SCHEMBL2572316 0.79 ALDH1A1 (0.37) ALDH1A1TSHRACHECYP2C19TDP1
SCHEMBL7047179 0.79 TSHR (0.44) ALDH1A1TSHRACHECYP2C19TDP1
SCHEMBL11072425 0.76 NPSR1 (0.37) ALDH1A1TSHRCYP2C19TDP1RAB9A
SCHEMBL6341579 0.76 ALDH1A1 (0.41) ALDH1A1TSHRACHECYP2C19TDP1
SCHEMBL28985472 0.73 RAB9A (0.36) ALDH1A1TSHRRAB9APOLB
SCHEMBL4179114 0.70 ALDH1A1 (0.50) ALDH1A1TSHRACHECYP2C19TDP1
P-Xylene SCHEMBL28247604 0.69 ACHE (0.50) ALDH1A1ACHETDP1GAALMNA
SCHEMBL9461590 0.69 ALDH1A1 (0.48) ALDH1A1TSHRACHECYP2C19TDP1
SCHEMBL145821 0.69 CYP2C19 (0.50) ALDH1A1TSHRACHECYP2C19TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1790323-B1 Dental polymerizable core build-up material of separately packed type KURARAY NORITAKE DENTAL INC (JP) 2016-03-23 EP disclosed
US-7820733-B2 Dental polymerizable core build-up material of separately packed type KURARAY MEDICAL INC. (JP) 2010-10-26 US disclosed
US-20070249752-A1 Dental Polymerizable Core Build-Up Material of Separately Packed Type KURARAY MEDICAL INC. (JP) 2007-10-25 US disclosed
EP-1790323-A1 DENTAL POLYMERIZABLE CORE BUILD-UP MATERIAL OF SEPARATELY PACKED TYPE Kuraray Medical Inc. (JP) 2007-05-30 EP disclosed
EP-0050996-B1 UNCURED FILLED COATING COMPOSITIONS AND CURED PRODUCTS THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-03-28 EP disclosed
US-4427823-A Cured or uncured filled coating composition of polyfunctional acrylic-type acid ester and utilization thereof MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1984-01-24 US disclosed
EP-0050996-A1 Uncured filled coating compositions and cured products thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-05-05 EP disclosed