Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659548 | 0.87 | NOD2 (0.57) | MTNR1AMTNR1BKMT2AMCL1NOD2 | |
| SCHEMBL16402064 | 0.84 | PLA2G10 (0.48) | KMT2AMCL1KDM4EALDH1A1CCR2 | |
| SCHEMBL29834903 | 0.75 | L3MBTL1 (0.67) | MTNR1AMTNR1BKMT2AMCL1KDM4E | |
| SCHEMBL4486403 | 0.75 | L3MBTL1 (0.67) | MTNR1AMTNR1BKMT2AMCL1KDM4E | |
| SCHEMBL4740170 | 0.75 | MTNR1A (0.53) | MTNR1AMTNR1BKMT2AMCL1NOD2 | |
| SCHEMBL7884242 | 0.75 | DAO (0.64) | MTNR1AMTNR1BKMT2AMCL1NOD2 | |
| SCHEMBL20969368 | 0.74 | NOD2 (0.55) | MTNR1AMTNR1BKMT2AMCL1NOD2 | |
| SCHEMBL7873282 | 0.74 | MTNR1A (0.56) | MTNR1AMTNR1BKMT2AMCL1NOD2 | |
| SCHEMBL27911009 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BKMT2AMCL1NOD2 | |
| SCHEMBL519307 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BKMT2AMCL1NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-B | Synthetic method of 2-substituted indole derivative | 中国医学科学院药物研究所 | 2021-12-07 | — | — | CN | disclosed |