SCHEMBL30388992

SCHEMBL30388992

COCc1ccc(-c2sc3ccccc3c2-c2c(O)c(C)nn(C)c2=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.49
TDP1 Q9NUW8 2/20 0.49
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSP90AA1 P07900 2/20 0.38
PTPN1 P18031 1/20 0.35
UBE2N P61088 1/20 0.35
PAX8 Q06710 1/20 0.35
ITGA4 P13612 1/20 0.34
MAPT P10636 2/20 0.34
ATM Q13315 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
PLA2G10 O15496 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25187858 1.00 L3MBTL1 (0.49) L3MBTL1TDP1MEN1KMT2ALMNA
SCHEMBL28665444 0.82 MEN1 (0.39) L3MBTL1MEN1KMT2AHSP90AA1UBE2N
SCHEMBL25199057 0.74 ESR1 (0.34) L3MBTL1TDP1LMNASMN1; SMN2HSP90AA1
SCHEMBL25184312 0.74 ESR1 (0.38) KDM4E
SCHEMBL30389735 0.74 ESR1 (0.38) KDM4E
SCHEMBL28666652 0.72 UBE2N (0.37) L3MBTL1TDP1MEN1KMT2AHSP90AA1
SCHEMBL29384893 0.72 UBE2N (0.37) L3MBTL1TDP1MEN1KMT2AHSP90AA1
SCHEMBL30254871 0.71 MIF (0.38) TP53
SCHEMBL28661730 0.70 GPR139 (0.35) HSP90AA1
SCHEMBL25181426 0.69 MC4R (0.41) HPGDKDM4ETSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265781-A Herbicide resistance 先正达农作物保护股份公司 2024-06-28 CN disclosed
WO-2023083972-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2023-05-19 WO disclosed