Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.73 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670959 | 0.82 | MAPT (0.50) | MAPTTHRBTP53LMNAGAA | |
| SCHEMBL28688178 | 0.82 | MAPT (0.51) | MAPTTHRBTP53LMNAGAA | |
| SCHEMBL28670963 | 0.82 | MAPT (0.64) | MAPTTHRBTP53LMNAGAA | |
| SCHEMBL28667847 | 0.81 | MAPT (0.56) | MAPTTHRBTP53LMNAGAA | |
| SCHEMBL28681669 | 0.80 | MAPT (0.56) | MAPTTHRBTP53LMNAGAA | |
| SCHEMBL28665720 | 0.79 | MAPT (0.54) | MAPTTHRBTP53LMNAGAA | |
| SCHEMBL28688233 | 0.79 | S1PR1 (0.56) | MAPTTHRBLMNAGAADRD2 | |
| SCHEMBL28665714 | 0.77 | MAPT (0.64) | MAPTTHRBTP53LMNAGAA | |
| SCHEMBL28667773 | 0.76 | MAPT (0.62) | MAPTTHRBTP53LMNAGAA | |
| SCHEMBL28665641 | 0.75 | MAPT (0.58) | MAPTTHRBTP53LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658889-B | 1,2, 4-oxadiazole-aryl piperazine compound containing naphthalene ring and preparation method and application thereof | 贵州医科大学 | 2021-12-17 | — | — | CN | disclosed |