Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688168 | 0.83 | MAPT (0.53) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL28670963 | 0.82 | MAPT (0.64) | MAPTTP53KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28665709 | 0.82 | MAPT (0.73) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL28665720 | 0.82 | MAPT (0.54) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL28680258 | 0.81 | MAPT (0.53) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL28688233 | 0.80 | S1PR1 (0.56) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28688178 | 0.78 | MAPT (0.51) | MAPTTP53ALDH1A1LMNATHRB | |
| SCHEMBL28665641 | 0.78 | MAPT (0.58) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL28930626 | 0.78 | MAPT (0.68) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL28681669 | 0.78 | MAPT (0.56) | MAPTTP53KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658889-B | 1,2, 4-oxadiazole-aryl piperazine compound containing naphthalene ring and preparation method and application thereof | 贵州医科大学 | 2021-12-17 | — | — | CN | disclosed |