Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688233 | 0.88 | S1PR1 (0.56) | MAPTLMNAGAATHRBDRD2 | |
| SCHEMBL28667773 | 0.83 | MAPT (0.62) | MAPTLMNAGAATHRBTP53 | |
| SCHEMBL28670959 | 0.82 | MAPT (0.50) | MAPTLMNAGAATHRBTP53 | |
| SCHEMBL28665714 | 0.82 | MAPT (0.64) | MAPTLMNAGAATHRBDRD2 | |
| SCHEMBL28665709 | 0.82 | MAPT (0.73) | MAPTLMNAGAATHRBDRD2 | |
| SCHEMBL28665720 | 0.79 | MAPT (0.54) | MAPTLMNAGAATHRBDRD3 | |
| SCHEMBL28688178 | 0.78 | MAPT (0.51) | MAPTLMNAGAATHRBTP53 | |
| SCHEMBL31546357 | 0.78 | MAPT (0.63) | MAPTLMNAGAATHRBTP53 | |
| SCHEMBL28681669 | 0.78 | MAPT (0.56) | MAPTLMNAGAATHRBSLC6A2 | |
| SCHEMBL28665641 | 0.75 | MAPT (0.58) | MAPTLMNAGAATHRBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658889-B | 1,2, 4-oxadiazole-aryl piperazine compound containing naphthalene ring and preparation method and application thereof | 贵州医科大学 | 2021-12-17 | — | — | CN | disclosed |