SCHEMBL2862889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861026	0.86	TNIK (0.49)	TNIKMAPK14MAPKAPK2NTRK1TRPV1
	SCHEMBL2867309	0.84	TNIK (0.44)	TNIKMAPK14MAPKAPK2MAPK10TUBB4A
	SCHEMBL2866231	0.81	MAPKAPK2 (0.47)	MAPKAPK2MAPK10FYNTUBB4ATUBB
	SCHEMBL2864750	0.81	CDK2 (0.43)	TNIKMAPKAPK2NTRK1JAK2JAK3
	SCHEMBL4335786	0.80	MAPK10 (0.52)	TNIKMAPKAPK2NTRK1MAPK10JAK2
	SCHEMBL2861862	0.80	TUBB4A (0.42)	MAPKAPK2MAPK10FYNTUBB4ATUBB
	SCHEMBL2867192	0.79	TNIK (0.41)	TNIKMAPK14MAPKAPK2MAPK10JAK2
	SCHEMBL2865310	0.79	TNIK (0.40)	TNIKMAPKAPK2MAPK10JAK2JAK3
	SCHEMBL4337647	0.79	STK33 (0.44)	TNIKMAPK14MAPK10
	SCHEMBL2857820	0.78	ACLY (0.42)	TNIKMAPKAPK2MAPK10ACLYTUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.