Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680120 | 0.93 | HSD17B10 (0.49) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL28673108 | 0.92 | HSD17B10 (0.52) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL28680108 | 0.86 | HSD17B10 (0.49) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL28665126 | 0.84 | ALDH1A1 (0.51) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL28683888 | 0.83 | SMN1; SMN2 (0.50) | KMT2AKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL28680979 | 0.80 | MEN1 (0.47) | KMT2AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL28667719 | 0.80 | ALDH1A1 (0.57) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL28290889 | 0.79 | KMT2A (0.62) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL28667095 | 0.79 | KMT2A (0.59) | KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL28670869 | 0.77 | KMT2A (0.52) | KMT2AKDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824574-B | Indole-3-carboxamides and their use | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |