Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673108 | 0.92 | HSD17B10 (0.52) | ALDH1A1HSD17B10LMNAKDM4EHPGD | |
| SCHEMBL28680120 | 0.92 | HSD17B10 (0.49) | ALDH1A1HSD17B10LMNAKDM4EHPGD | |
| SCHEMBL28667737 | 0.84 | KMT2A (0.53) | ALDH1A1HSD17B10LMNAKDM4EHPGD | |
| SCHEMBL28683883 | 0.84 | FKBP1A (0.53) | ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL28670860 | 0.83 | KDM4E (0.51) | ALDH1A1HSD17B10LMNAKDM4EHPGD | |
| SCHEMBL28671863 | 0.80 | HTT (0.52) | ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL28667098 | 0.80 | GAA (0.48) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| SCHEMBL28688994 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HSD17B10LMNAKDM4EHPGD | |
| SCHEMBL28290888 | 0.77 | RAB9A (0.47) | ALDH1A1HSD17B10LMNAHPGDMAPK1 | |
| SCHEMBL28289454 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HSD17B10LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824574-B | Indole-3-carboxamides and their use | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |