SCHEMBL28668320

SCHEMBL28668320

C=C(CC(=O)Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O)C(=O)NCCOCCOCCOCCN=[N+]=[N-]

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.53
▸ MAP1LC3B Q9GZQ8 7/20 0.48
▸ CRBN Q96SW2 10/20 0.46
▸ BRD4 O60885 2/20 0.45
▸ GSPT1 P15170 2/20 0.45
▸ CSNK1A1 P48729 2/20 0.45
▸ SALL4 Q9UJQ4 2/20 0.45
▸ IKZF3 Q9UKT9 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30550160 0.90 MAP1LC3B (0.59) STAT3MAP1LC3BCRBNBRD4GSPT1
SCHEMBL25376586 0.90 MAP1LC3B (0.59) STAT3MAP1LC3BCRBNBRD4GSPT1
SCHEMBL30891811 0.89 STAT3 (0.53) STAT3MAP1LC3BCRBNBRD4
SCHEMBL30891789 0.89 STAT3 (0.53) STAT3MAP1LC3BCRBNBRD4
SCHEMBL23772825 0.88 MAP1LC3B (0.51) STAT3MAP1LC3BCRBNBRD4IKZF3
SCHEMBL25031848 0.88 MAP1LC3B (0.52) STAT3MAP1LC3BCRBNBRD4GSPT1
SCHEMBL23772670 0.88 MAP1LC3B (0.51) STAT3MAP1LC3BCRBNBRD4IKZF3
SCHEMBL23772439 0.88 MAP1LC3B (0.51) STAT3MAP1LC3BCRBNBRD4IKZF3
SCHEMBL25756460 0.88 MAP1LC3B (0.52) STAT3MAP1LC3BCRBNBRD4GSPT1
SCHEMBL23037219 0.87 CRBN (0.52) MAP1LC3BCRBNBRD4IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113663067-B Immune activated antibody and application thereof 深圳市康居正医药科技有限公司 2025-06-17 — — CN disclosed
CN-113663067-A Immune activation type antibody and application thereof 深圳市康居正医药科技有限公司 2021-11-19 — — CN disclosed
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