SCHEMBL28668461

SCHEMBL28668461

ClC=CC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.43
KCNN4 O15554 5/20 0.38
ALDH1A1 P00352 4/20 0.38
CYP1A2 P05177 1/20 0.36
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 1/20 0.31
HTT P42858 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151065 0.75 MAPK1 (0.41) TSHRKCNN4ALDH1A1CYP1A2MAPK1
SCHEMBL28532502 0.74 TSHR (0.38) TSHRKCNN4ALDH1A1CYP1A2MAPK1
SCHEMBL946821 0.74 KCNN4 (0.39) TSHRKCNN4ALDH1A1MAPK1KDM4E
SCHEMBL11879399 0.73 TSHR (0.44) TSHRKCNN4ALDH1A1CYP1A2MAPK1
SCHEMBL2953826 0.73 TSHR (0.39) TSHRKCNN4ALDH1A1CYP1A2MAPK1
SCHEMBL2953828 0.73 TSHR (0.39) TSHRKCNN4ALDH1A1CYP1A2MAPK1
SCHEMBL11879395 0.73 TSHR (0.44) TSHRKCNN4ALDH1A1CYP1A2MAPK1
SCHEMBL912658 0.72 ALDH1A1 (0.41) TSHRKCNN4ALDH1A1CYP1A2MAPK1
SCHEMBL4446279 0.72 MAOB (0.48) TSHRALDH1A1CYP1A2MAPK1
Ammonia Solution, Strong SCHEMBL6679103 0.70 ALDH1A1 (0.39) TSHRKCNN4ALDH1A1CYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113677400-A Dual mode radiotracers and therapeutic agents that bind PSMA 慕尼黑工业大学 2021-11-19 CN disclosed