Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11879395 | 0.79 | TSHR (0.44) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL11879399 | 0.79 | TSHR (0.44) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL10382218 | 0.78 | MAPK1 (0.42) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL95942 | 0.76 | MAPK1 (0.41) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL95943 | 0.76 | MAPK1 (0.41) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL28668461 | 0.75 | TSHR (0.43) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL737574 | 0.75 | MAPK1 (0.44) | MAPK1TSHRALDH1A1TAAR1ALOX15 | |
| SCHEMBL6546422 | 0.74 | CYP2C19 (0.50) | MAPK1TSHRALDH1A1CYP2C19 | |
| SCHEMBL4789182 | 0.74 | CYP2C19 (0.50) | MAPK1TSHRALDH1A1CYP2C19 | |
| SCHEMBL9858424 | 0.73 | ALDH1A1 (0.41) | MAPK1TSHRALDH1A1TAAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166616-B2 | Substituted alkanoic acids | AVENTIS PHARMA LIMITED (GB) | 2007-01-23 | — | — | US | disclosed |
| EP-1409440-A4 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM & HAAS (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1409440-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002068367-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |