SCHEMBL912658

SCHEMBL912658

C=CC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
TSHR P16473 4/20 0.41
KCNN4 O15554 3/20 0.41
HTT P42858 1/20 0.38
MAPK1 P28482 1/20 0.36
KDM4E B2RXH2 1/20 0.33
AKT1 P31749 1/20 0.33
CYP1A2 P05177 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
ALOX15 P16050 1/20 0.33
PTPN1 P18031 1/20 0.32
ESR1 P03372 1/20 0.32
CYP3A4 P08684 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL6679103 0.97 ALDH1A1 (0.39) ALDH1A1TSHRKCNN4HTTMAPK1
SCHEMBL28980121 0.90 TSHR (0.35) ALDH1A1TSHRKCNN4HTTMAPK1
SCHEMBL5469904 0.86 ESR1 (0.54) ALDH1A1TSHRESR1CYP3A4ESR2
SCHEMBL8457643 0.81 CA4 (0.48) ALDH1A1TSHRALOX15CYP3A4
SCHEMBL5408655 0.79 ALDH1A1 (0.45) ALDH1A1TSHRKCNN4HTTKDM4E
SCHEMBL1064377 0.79 TSHR (0.43) ALDH1A1TSHRKCNN4HTTMAPK1
SCHEMBL4905365 0.78 TSHR (0.38) ALDH1A1TSHRKCNN4HTTMAPK1
SCHEMBL11780250 0.78 ALDH1A1 (0.43) ALDH1A1TSHRKCNN4HTTKDM4E
SCHEMBL1587335 0.77 ALDH1A1 (0.41) ALDH1A1TSHRKCNN4HTTMAPK1
SCHEMBL16933814 0.74 ALDH1A1 (0.39) ALDH1A1TSHRKCNN4HTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868118-B2 High refractive index flexible silicone OPHTEC B.V. (NL) 2011-01-11 US claimed
US-20070203317-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE OPHTEC B.V. (NL) 2007-08-30 US claimed
EP-1472305-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE Ophtec B.V. (NL) 2004-11-03 EP claimed
US-20030162929-A1 High refractive index flexible silicone OPHTEC B.V. (NL) 2003-08-28 US claimed
WO-2003066707-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE OPHTEC B.V. (NL) 2003-08-14 WO claimed
EP-1334991-A1 High refractive index flexible silicone Ophtec B.V. (NL) 2003-08-13 EP claimed
US-12570774-B2 Cycloolefin resin cured product having oxygen barrier properties RIMTEC CORPORATION (JP) 2026-03-10 US disclosed
EP-4703402-A1 POLYMERIZABLE COMPOSITION AND MOLDED ARTICLE RIMTEC Corporation (JP) 2026-03-04 EP disclosed
EP-3960414-B1 METHOD FOR PRODUCING CYCLOOLEFIN RESIN-DECORATIVE MOLDED ARTICLE RIMTEC CORP (JP) 2025-08-06 EP disclosed
US-12343905-B2 Method for producing cycloolefin resin-decorative molded article RIMTEC CORPORATION (JP) 2025-07-01 US disclosed
WO-2024224997-A1 POLYMERIZABLE COMPOSITION AND MOLDED ARTICLE RIMTEC株式会社 2024-10-31 WO disclosed
US-20240287234-A1 COMPOSITE MATERIAL AND MOLDED COMPOSITE MATERIAL RIMTEC CORPORATION (JP) 2024-08-29 US disclosed
US-12012474-B2 Composite material and molded composite material RIMTEC CORPORATION (JP) 2024-06-18 US disclosed
WO-2000056785-A1 OLEFIN POLYMERIZATION CATALYSTS AND PROCESSES FOR MAKING AND USING SAME CRYOVAC, INC. (US) 2000-09-28 WO disclosed
US-4994539-A Ethylene-unsaturated aromatic copolymer NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-19 US disclosed
EP-0180771-B1 METHOD FOR IMPROVING IMPULSE BREAKDOWN STRENGTH OF ELECTRICALLY INSULATING MATERIALS Nippon Petrochemicals Co., Ltd. (JP) 1989-08-02 EP disclosed
US-4734824-A MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-29 US disclosed
EP-0154993-B1 ELECTRICAL INSULATING OIL AND ELECTRICAL APPLIANCES IMPREGNATED WITH THE SAME NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-09 EP disclosed
US-4621302-A MONO-OR DIOLEFIN HAVING THREE CONDENSED OR NON-CONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-11-04 US disclosed
EP-0154993-A1 Electrical insulating oil and electrical appliances impregnated with the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203317-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE MACF1, SMCHD1, RPIA ALDH1A1 1321/4885TSHR 4289/4885KCNN4 1463/4885
US-12570774-B2 Cycloolefin resin cured product having oxygen barrier properties HMOX1, GPX1, ALOX12 ALDH1A1 467/4885TSHR 4714/4885KCNN4 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.