Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28681813 | 0.85 | MAPT (0.50) | KMT2ARAB9ANPC1MAPTPTPN2 | |
| SCHEMBL28544876 | 0.84 | MAPT (0.53) | RAB9ANPC1MAPTPTPN2PTPN1 | |
| SCHEMBL30619952 | 0.84 | MAPT (0.53) | RAB9ANPC1MAPTPTPN2PTPN1 | |
| SCHEMBL28688356 | 0.81 | NPC1 (0.53) | KMT2ARAB9ANPC1GFERMAPT | |
| SCHEMBL28688484 | 0.81 | BCHE (0.54) | KMT2ARAB9ANPC1MAPTPTPN2 | |
| SCHEMBL7108873 | 0.75 | SMN1; SMN2 (0.69) | KMT2ARAB9ANPC1GFERMAPT | |
| SCHEMBL7336243 | 0.74 | MAPT (0.63) | RAB9ANPC1GFERMAPTLMNA | |
| SCHEMBL28692097 | 0.73 | ALDH1A1 (0.54) | RAB9ANPC1MAPTPTPN2PTPN1 | |
| SCHEMBL28665946 | 0.72 | MAPT (0.49) | KMT2ARAB9ANPC1GFERMAPT | |
| SCHEMBL28546894 | 0.71 | KMT2A (1.00) | KMT2ARAB9ANPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574949-B | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2021-12-24 | — | — | CN | disclosed |