Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28692097 | 0.85 | ALDH1A1 (0.54) | NPC1MAPTRAB9ALMNATP53 | |
| SCHEMBL30619952 | 0.85 | MAPT (0.53) | BCHENPC1MAPTRAB9ALMNA | |
| SCHEMBL28544876 | 0.85 | MAPT (0.53) | BCHENPC1MAPTRAB9ALMNA | |
| SCHEMBL28688356 | 0.85 | NPC1 (0.53) | BCHENPC1MAPTRAB9ALMNA | |
| SCHEMBL28668490 | 0.81 | KMT2A (0.55) | BCHENPC1MAPTRAB9ALMNA | |
| SCHEMBL10849069 | 0.76 | TP53 (0.83) | NPC1MAPTRAB9ALMNATP53 | |
| SCHEMBL28665946 | 0.75 | MAPT (0.49) | BCHENPC1MAPTRAB9ALMNA | |
| SCHEMBL6902568 | 0.74 | NPC1 (0.63) | BCHENPC1MAPTRAB9ALMNA | |
| SCHEMBL7336243 | 0.74 | MAPT (0.63) | NPC1MAPTRAB9ALMNATP53 | |
| SCHEMBL18901151 | 0.74 | NPC1 (0.63) | NPC1MAPTRAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574949-B | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2021-12-24 | — | — | CN | disclosed |