Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862183 | 0.89 | EPHX2 (0.44) | EPHX2MAPT | |
| SCHEMBL10042986 | 0.88 | EPHX2 (0.54) | EPHX2MAPTTHRB | |
| SCHEMBL2865945 | 0.87 | EPHX2 (0.46) | EPHX2MAPT | |
| SCHEMBL2861378 | 0.86 | EPHX2 (0.45) | EPHX2MAPT | |
| SCHEMBL2854987 | 0.85 | MAPT (0.47) | EPHX2DYRK1AMAPTPOLBF2R | |
| SCHEMBL543875 | 0.85 | EPHX2 (0.45) | EPHX2DYRK1AMAPT | |
| SCHEMBL2861770 | 0.84 | EPHX2 (0.46) | EPHX2MAPT | |
| SCHEMBL2864350 | 0.83 | EPHX2 (0.45) | EPHX2DYRK1APOLB | |
| SCHEMBL2860311 | 0.83 | EPHX2 (0.41) | EPHX2DYRK1AMAPTPOLB | |
| SCHEMBL2859668 | 0.83 | GSK3B (0.37) | EPHX2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802695-B1 | POLY(ARYLETHERDISULFONE) COMPOSITION AND SHAPED ARTICLE MADE THEREOF | SOLVAY SPECIALTY POLYMERS USA (US) | 2013-05-01 | — | — | EP | claimed |
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |
| US-7709510-B2 | Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-05-04 | — | — | US | claimed |
| US-20040092503-A1 | Azoles as malonyl-coa decarboxylase inhibitors useful as metabolic modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-05-13 | — | — | US | claimed |
| EP-1370260-A2 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-12-17 | — | — | EP | claimed |
| WO-2002066035-A2 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-08-29 | — | — | WO | claimed |
| EP-3854921-A1 | PARTIAL FLOAT WEAVE FABRIC | Milliken & Company (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3380659-B1 | PARTIAL FLOAT WEAVE FABRIC | MILLIKEN & CO (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3380659-A1 | PARTIAL FLOAT WEAVE FABRIC | Milliken & Company (US) | 2018-10-03 | — | — | EP | disclosed |
| EP-2278051-B1 | Improved fabrics | SOLVAY SPECIALTY POLYMERS USA (US) | 2012-12-05 | — | — | EP | disclosed |
| EP-2140047-A2 | IMPROVED FABRICS | Solvay Advanced Polymers, L.L.C. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008116844-A2 | IMPROVED FABRICS | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092503-A1 | Azoles as malonyl-coa decarboxylase inhibitors useful as metabolic modulators | ME1, ME3, ME2 | EPHX2 1552/4885DYRK1A 1717/4885MAPT 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.