Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999684 | 0.69 | ALDH1A1 (0.39) | CDK2FLT3CCNA1IRAK4ROCK2 | |
| SCHEMBL2713361 | 0.69 | LMNA (0.45) | SMN1; SMN2ROCK2 | |
| SCHEMBL2713357 | 0.69 | LMNA (0.45) | SMN1; SMN2ROCK2 | |
| SCHEMBL16168690 | 0.69 | DPP4 (0.40) | SMN1; SMN2ROCK2 | |
| SCHEMBL30680099 | 0.68 | ALDH1A1 (0.42) | HRH3SMN1; SMN2 | |
| SCHEMBL24373917 | 0.68 | ALDH1A1 (0.42) | HRH3SMN1; SMN2 | |
| SCHEMBL31332215 | 0.68 | CHKA (0.32) | — | |
| SCHEMBL2708036 | 0.68 | WNT3A (0.41) | — | |
| Bromide SCHEMBL309082 | 0.68 | LMNA (0.44) | ROCK2 | |
| Bromide SCHEMBL2711090 | 0.68 | LMNA (0.44) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727758-A | Bicyclic heterocyclic compounds and use thereof | 锐新医药公司 | 2021-11-30 | — | — | CN | disclosed |