Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664281 | 0.91 | LMNA (0.34) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL28658947 | 0.90 | KCNH2 (0.37) | MEN1KMT2ACACNA1HCYP2D6KCNH2 | |
| SCHEMBL28670634 | 0.89 | LMNA (0.32) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL28676235 | 0.81 | ALDH1A1 (0.38) | MEN1KMT2ACACNA1HCYP2D6KCNH2 | |
| SCHEMBL28664287 | 0.81 | CACNA1H (0.39) | MEN1KMT2ACACNA1HCYP2D6KCNH2 | |
| SCHEMBL28670645 | 0.80 | MEN1 (0.37) | MEN1KMT2ACACNA1HCYP2D6KCNH2 | |
| SCHEMBL28668464 | 0.80 | KCNH2 (0.36) | MEN1KMT2ACACNA1HCYP2D6KCNH2 | |
| SCHEMBL28658945 | 0.80 | KCNH2 (0.36) | MEN1KMT2ACACNA1HCYP2D6KCNH2 | |
| SCHEMBL28668938 | 0.79 | SMPD1 (0.36) | MAPTMAPK14KCNH2ABCG2HDAC1 | |
| SCHEMBL28655462 | 0.78 | GRN (0.38) | MAPTMEN1KMT2ACACNA1HCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |