Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28687678 | 0.84 | ALDH1A1 (0.37) | ESR1TSHRSLC6A2HTR2CCYP2C19 | |
| SCHEMBL704522 | 0.78 | ESR1 (0.52) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL8082747 | 0.78 | ESR1 (0.62) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL705169 | 0.73 | ESR1 (0.47) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL12124965 | 0.71 | ESR1 (0.48) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL1608613 | 0.69 | — | — | |
| SCHEMBL9229753 | 0.68 | ESR1 (0.45) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL8750626 | 0.68 | ESR1 (0.50) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL28693709 | 0.68 | FFAR1 (0.37) | ADRA2AADRA2BADRA2C | |
| SCHEMBL15854157 | 0.68 | ESR1 (0.54) | ESR1ADRA2AADRA2BADRA2CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250754-B | Silicon-containing resin composition, silicon-containing resin film, silica film, light-emitting display element panel, and light-emitting display device | 东京应化工业株式会社 | 2022-01-25 | — | — | CN | disclosed |