Formic Acid

Formic Acid

SCHEMBL2867086

CCCCCCN(CCCCCC)CCCCCC.O=CO

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.46
KDM5A P29375 3/20 0.46
PHF8 Q9UPP1 2/20 0.46
KDM4C Q9H3R0 1/20 0.46
ADH1C P00326 2/20 0.45
ADH1A P07327 2/20 0.45
ADH4 P08319 2/20 0.45
TSHR P16473 2/20 0.44
ICMT O60725 1/20 0.42
ALB P02768 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
EPHX1 P07099 1/20 0.41
ADH1B P00325 1/20 0.41
ADH7 P40394 1/20 0.41
S1PR2 O95136 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28121779 1.00 DNM1 (0.46) DNM1KDM5APHF8KDM4CADH1C
Formic Acid SCHEMBL27919924 0.91 KCNH2 (0.43) DNM1KDM5APHF8KDM4CADH1C
Formic Acid SCHEMBL2368233 0.90 CA12 (0.46) KDM5APHF8KDM4CADH1CADH1A
Formic Acid SCHEMBL9721362 0.87 CA12 (0.44) KDM5APHF8KDM4CADH1CADH1A
Methyl Alcohol SCHEMBL10977238 0.84 DNM1 (0.55) DNM1KDM5APHF8KDM4CTSHR
SCHEMBL24187667 0.84 DNM1 (0.61) DNM1KDM5APHF8KDM4CTSHR
SCHEMBL3820220 0.84 DNM1 (0.61) DNM1KDM5APHF8KDM4CTSHR
Octane SCHEMBL2485910 0.84 TSHR (0.58) ADH1CADH1AADH4TSHREPHX1
SCHEMBL17599247 0.84 DNM1 (0.61) DNM1KDM5APHF8KDM4CTSHR
SCHEMBL11804291 0.84 DNM1 (0.61) DNM1KDM5APHF8KDM4CTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901350-B2 Process for the preparation of formic acid BASF SE (DE) 2014-12-02 US disclosed
CN-102574762-B Method for producing formic acid SCHAUB THOMAS 2014-08-13 CN disclosed
CN-103974927-A Method for producing formic acid by reacting carbon dioxide with hydrogen BASF SE 2014-08-06 CN disclosed
US-8426641-B2 Process for preparing formic acid BASF SE (DE) 2013-04-23 US disclosed
US-20130090496-A1 PROCESS FOR PREPARING FORMIC ACID BY REACTING CARBON DIOXIDE WITH HYDROGEN BASF SE (DE) 2013-04-11 US disclosed
CN-102574762-A Method for producing formic acid THOMAS SCHAUB 2012-07-11 CN disclosed
US-20110319657-A1 Process for the Preparation of Formic Acid BASF SE (DE) 2011-12-29 US disclosed
US-20100331573-A1 PROCESS FOR PREPARING FORMIC ACID BASF SE (DE) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331573-A1 PROCESS FOR PREPARING FORMIC ACID F2, TAF9, HAO2 DNM1 3509/4885KDM5A 1936/4885PHF8 905/4885
US-20130090496-A1 PROCESS FOR PREPARING FORMIC ACID BY REACTING CARBON DIOXIDE WITH HYDROGEN CA1, CA3, HAO2 DNM1 1646/4885KDM5A 984/4885PHF8 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.