Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LIPE | Q05469 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30950209 | 0.84 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28864240 | 0.81 | ALDH1A1 (0.76) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30632968 | 0.80 | ALDH1A1 (0.72) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27722718 | 0.79 | ALDH1A1 (0.62) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1532689 | 0.78 | ALDH1A1 (0.60) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30541505 | 0.77 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19066192 | 0.76 | ALDH1A1 (0.67) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26123763 | 0.76 | ALDH1A1 (0.67) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL5266041 | 0.76 | ALDH1A1 (0.57) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31596236 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290881-B | Therapeutic compounds and methods of use thereof | 健泰科生物技术公司 | 2021-12-07 | — | — | CN | disclosed |