Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670891 | 0.84 | ALDH1A1 (0.64) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28864238 | 0.83 | ALDH1A1 (0.51) | ALDH1A1POLBSIGMAR1SMN1; SMN2MEN1 | |
| SCHEMBL29988703 | 0.81 | MKNK1 (0.52) | ALDH1A1POLBMKNK1MKNK2SMN1; SMN2 | |
| SCHEMBL12271108 | 0.81 | MKNK1 (0.52) | ALDH1A1POLBMKNK1MKNK2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1532934 | 0.79 | MKNK1 (0.51) | ALDH1A1MKNK1MKNK2KMT2A | |
| SCHEMBL19066133 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBTPSAB1TPSD1TPSG1 | |
| SCHEMBL17293693 | 0.77 | ALDH1A1 (0.45) | ALDH1A1POLBTPSAB1TPSD1TPSG1 | |
| SCHEMBL20448931 | 0.76 | ALDH1A1 (0.43) | ALDH1A1POLBTPSAB1TPSD1TPSG1 | |
| SCHEMBL2583030 | 0.76 | GAA (0.61) | ALDH1A1POLBSIGMAR1SMN1; SMN2MEN1 | |
| SCHEMBL27973539 | 0.75 | TRPA1 (0.44) | ALDH1A1POLBTPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |