SCHEMBL2867237

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2870409	0.87	JAK2 (0.56)	DYRK1AABL1BCRALDH1A1MAPK10
	SCHEMBL2864990	0.82	CYP3A4 (0.54)	ABL1BCRALDH1A1MAPK1MEN1
	SCHEMBL31172167	0.80	ALDH1A1 (0.51)	MAP4K1ALDH1A1MAPTMAPK10FLT3
	SCHEMBL2858476	0.79	MAP2K4 (0.68)	MAPK1NTRK1
	SCHEMBL5376946	0.78	MAPK8 (0.54)	MAP4K1DYRK1AMAPK10MAP4K4KDM4E
	SCHEMBL5801740	0.78	MAP2K4 (0.65)	MAPK1MAPK10NTRK1
	SCHEMBL2860913	0.78	MAP2K4 (0.61)	MAPTMAPK1MEN1KMT2ANTRK1
	SCHEMBL5378619	0.78	ABL1 (0.57)	ABL1BCRALDH1A1MAPTMAPK1
	Ethylene SCHEMBL27536148	0.77	MAP2K4 (0.65)	MAPK1NTRK1
	SCHEMBL1225812	0.76	PDPK1 (0.61)	MAPK10FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.