Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 13/20 | 0.81 |
| ▸ | IDO1 | P14902 | 8/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249092 | 0.90 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL19249001 | 0.86 | TDO2 (0.81) | TDO2IDO1 | |
| SCHEMBL19249225 | 0.80 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL19249005 | 0.76 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL19249224 | 0.75 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL19249003 | 0.74 | TDO2 (1.00) | TDO2IDO1CYP1A2 | |
| SCHEMBL19249008 | 0.74 | TDO2 (0.74) | TDO2IDO1 | |
| SCHEMBL4348617 | 0.73 | MEN1 (0.53) | TDO2CNR1CNR2HDAC1HDAC6 | |
| SCHEMBL13122375 | 0.73 | ROCK2 (0.61) | TDO2MEN1KMT2A | |
| SCHEMBL5022794 | 0.73 | TRPV1 (0.72) | TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107840826-B | 1H-indazole derivatives and application thereof as IDO (intermediate bonded oxygen) inhibitor | 西华大学 | 2021-07-09 | — | — | CN | disclosed |