SCHEMBL2860104

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2867324	0.86	PIM1 (0.56)	PIM1PIM3PIM2MAP2K4MAPK1
	SCHEMBL5373231	0.85	PIM1 (0.58)	PIM1PIM3PIM2MAP2K4MAPK1
	SCHEMBL2861069	0.84	ALPL (0.54)	MAP2K4ALPLMAPK1MAPK3KDM4E
	SCHEMBL2866668	0.81	ALOX15 (0.44)	ALOX15HTTMAP2K4ALPLMAPK1
	SCHEMBL2857271	0.79	MAPK1 (0.46)	ALOX15HTTMAP2K4MAPK1MAPK3
	SCHEMBL2864413	0.78	MAP2K4 (0.60)	PIM1PIM3PIM2MAP2K4DYRK1A
	SCHEMBL2863569	0.78	LRRK2 (0.56)	PIM1PIM3PIM2ALOX15HTT
	SCHEMBL9986229	0.77	MAPK1 (0.58)	MAP2K4MAPK1MAPK3
	SCHEMBL2867251	0.77	FGFR1 (0.54)	MAP2K4MAPK1KDM4ENPC1ALDH1A1
	SCHEMBL2860913	0.77	MAP2K4 (0.61)	MAP2K4MAPK1MAPK3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.