SCHEMBL2867353

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5379414	0.74	ITK (0.53)	ITKLRRK2MAPKAPK2CYP1A2TTK
	SCHEMBL7091365	0.74	AURKA (0.65)	ITKAURKAAURKBTTKMAPK8
	SCHEMBL5372815	0.73	MAP2K4 (0.56)	ITKMAPKAPK2AURKAAURKBTTK
	SCHEMBL2447934	0.72	MET (0.64)	—
	SCHEMBL5388114	0.71	MAP2K4 (0.56)	LRRK2MAPKAPK2TTKMAPK8MAPK1
	SCHEMBL5383405	0.71	TTK (0.54)	ITKAURKAAURKBTTKMAPK8
	SCHEMBL6501210	0.70	AURKA (0.51)	ITKAURKAAURKBTTKMAPK8
	SCHEMBL16310072	0.70	RAB9A (0.59)	LRRK2MAPKAPK2CLK2CLK3DYRK1A
	SCHEMBL5374376	0.70	MAPT (0.55)	ITKAURKAAURKBTTKMAPK8
	SCHEMBL24150193	0.70	AURKA (0.65)	ITKLRRK2AURKAAURKBWNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.