Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.38 |
| ▸ | TOP1 | P11387 | 4/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CYCS | P99999 | 4/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683441 | 0.93 | TERT (0.39) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL28680656 | 0.89 | TERT (0.39) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL28673916 | 0.89 | ABCG2 (0.42) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL28671049 | 0.85 | CYCS (0.43) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL28689712 | 0.82 | TERT (0.40) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL28675065 | 0.80 | CYCS (0.43) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL28665759 | 0.78 | ABCG2 (0.42) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL28675077 | 0.77 | CYCS (0.36) | TERTTOP1ABCG2CYCS | |
| SCHEMBL28689706 | 0.76 | TERT (0.44) | TERTTOP1ABCG2CYCSENPP2 | |
| SCHEMBL28684338 | 0.76 | TERT (0.44) | TERTTOP1ABCG2CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | disclosed |