Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYCS | P99999 | 4/20 | 0.36 |
| ▸ | TERT | O14746 | 5/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28667155 | 0.88 | CYCS (0.36) | CYCSTERTABCG2DYRK3MAP4K4 | |
| SCHEMBL28673916 | 0.88 | ABCG2 (0.42) | CYCSTERTABCG2TOP1 | |
| SCHEMBL28680655 | 0.83 | CYCS (0.38) | CYCSABCG2HDAC6HDAC3HDAC4 | |
| SCHEMBL17687648 | 0.81 | TERT (0.43) | TERTABCG2CLK4 | |
| SCHEMBL28683441 | 0.78 | TERT (0.39) | CYCSTERTABCG2TOP1 | |
| SCHEMBL28673929 | 0.77 | TERT (0.38) | CYCSTERTABCG2TOP1 | |
| SCHEMBL6843058 | 0.76 | CYP1A2 (0.48) | TERT | |
| SCHEMBL28665759 | 0.76 | ABCG2 (0.42) | CYCSTERTABCG2TOP1 | |
| SCHEMBL14806849 | 0.74 | MAOA (0.40) | CYCSTERTHDAC6HDAC3HDAC4 | |
| SCHEMBL584884 | 0.74 | TSHR (0.47) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | disclosed |