Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | AHR | P35869 | 2/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816389 | 0.88 | TBK1 (0.56) | TBK1KDM4EHPGDGLAALDH1A1 | |
| SCHEMBL2761273 | 0.88 | TBK1 (0.52) | TBK1KDM4EHPGDGLAALDH1A1 | |
| SCHEMBL26674858 | 0.86 | TBK1 (0.81) | TBK1KDM4EHPGDGLAALDH1A1 | |
| SCHEMBL23260298 | 0.84 | TBK1 (0.49) | TBK1KDM4EHPGDGLAALDH1A1 | |
| SCHEMBL8964810 | 0.82 | ALDH1A1 (0.60) | KDM4EHPGDALDH1A1GAAAHR | |
| Dibenzofuran SCHEMBL9651343 | 0.80 | KDM4E (0.61) | KDM4EHPGDGLAALDH1A1TTR | |
| Dibenzofuran SCHEMBL7810840 | 0.80 | KDM4E (0.61) | KDM4EHPGDGLAALDH1A1TTR | |
| SCHEMBL20793652 | 0.79 | GPR35 (0.51) | TBK1KDM4EHPGDGLAALDH1A1 | |
| SCHEMBL16714053 | 0.78 | TTR (0.84) | TBK1KDM4EHPGDALDH1A1GAA | |
| SCHEMBL1222307 | 0.78 | TTR (0.78) | KDM4EHPGDGLAALDH1A1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108239054-B | Preparation method of benzofuran-3-carboxylic acid | 上海奥博生物医药股份有限公司 | 2022-01-21 | — | — | CN | disclosed |