SCHEMBL28674345

SCHEMBL28674345

CCCCOC1(C)C=CC(C)(OCCCC)N1Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.38
POLB P06746 1/20 0.37
ELANE P08246 2/20 0.37
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 1/20 0.35
NPC1 O15118 1/20 0.35
TLR7 Q9NYK1 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28674344 0.80 MMP1 (0.38) LTA4HELANEALDH1A1TSHRCYP3A4
SCHEMBL4482455 0.68 ELANE (0.42) ELANEALDH1A1TSHRTDP1L3MBTL1
SCHEMBL317686 0.63 TSHR (0.58) LTA4HALDH1A1TSHRCYP3A4MAPK1
SCHEMBL1922770 0.63 ELANE (0.47) POLBELANEALDH1A1TSHRNPSR1
SCHEMBL144042 0.61 ALDH1A1 (0.54) LTA4HALDH1A1TSHRTDP1L3MBTL1
SCHEMBL29098435 0.61 TSHR (0.56) LTA4HALDH1A1TSHRCYP3A4MAPK1
SCHEMBL27961981 0.61 TSHR (0.56) LTA4HALDH1A1TSHRCYP3A4MAPK1
SCHEMBL9621057 0.61 SIGMAR1 (0.48) LTA4HALDH1A1TSHRCYP3A4MAPK1
SCHEMBL27530835 0.61 TSHR (0.56) LTA4HALDH1A1TSHRCYP3A4MAPK1
SCHEMBL3438768 0.61 HRH3 (0.57) ALDH1A1TDP1L3MBTL1SIGMAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113897627-B Method for electrochemically preparing five-membered heterocyclic dialkoxy compound 万华化学集团股份有限公司 2023-03-03 CN disclosed
CN-113897627-A Method for electrochemically preparing five-membered heterocyclic dialkoxy compound 万华化学集团股份有限公司 2022-01-07 CN disclosed