SCHEMBL2867437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2863237	0.91	CSNK1D (0.52)	CSNK1DMAP2K4DGAT2MAPK1MAPK3
	SCHEMBL2870798	0.88	NTRK1 (0.52)	CSNK1DDGAT2KMT2AMAPK1
	SCHEMBL13635746	0.86	CSNK1D (0.49)	CSNK1DMAP2K4DGAT2MAPK1MAPK3
	SCHEMBL13198273	0.86	DGAT2 (0.50)	CSNK1DDGAT2MAPK1WNT1DYRK1A
	SCHEMBL2862635	0.84	DGAT2 (0.56)	CSNK1DDGAT2NPC1
	SCHEMBL2870355	0.84	MAPK1 (0.50)	CSNK1DMAP2K4MAPK1MAPK3
	SCHEMBL4332113	0.83	KDM4E (0.52)	MAP2K4KMT2APTAFRMAPK1MAP2K7
	SCHEMBL2863001	0.79	NTRK1 (0.56)	CSNK1DMAP2K4DGAT2MAPK1MAPK3
	SCHEMBL4333984	0.78	PTAFR (0.51)	KMT2APTAFRMAPK1MAPK3
	SCHEMBL4341451	0.78	KDM4E (0.49)	MAP2K4KMT2APTAFRMAPK1MAP2K7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.