Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 2/20 | 0.51 |
| ▸ | ACACA | Q13085 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28238507 | 0.81 | PTGES (0.54) | CACNA1BKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28096943 | 0.80 | CYP2C9 (0.46) | KDM4EALDH1A1LMNASMN1; SMN2FAAH | |
| SCHEMBL14066695 | 0.79 | CACNA1B (0.53) | CACNA1BKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12652785 | 0.79 | KDM4E (0.67) | CACNA1BKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25080975 | 0.77 | CACNA1B (0.54) | CACNA1BKDM4EACACBACACAPTGES | |
| SCHEMBL14347947 | 0.77 | ALOX5 (0.53) | CACNA1BKDM4EPTGESALOX5PPARG | |
| SCHEMBL28035866 | 0.77 | CYSLTR2 (0.58) | CACNA1BKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14119424 | 0.76 | TSHR (0.51) | CACNA1BKDM4EACACBACACAPTGES | |
| SCHEMBL16950919 | 0.76 | TSHR (0.51) | CACNA1BKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL26696139 | 0.76 | TSHR (0.53) | CACNA1BKDM4ESMN1; SMN2PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784944-A | Process for producing substituted 2- [2- (phenyl) ethylamino ] alkanamide derivatives | 纽朗制药公司 | 2021-12-10 | — | — | CN | disclosed |