Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 8/20 | 0.39 |
| ▸ | TEK | Q02763 | 7/20 | 0.39 |
| ▸ | SRC | P12931 | 6/20 | 0.39 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28677115 | 0.85 | SRC (0.54) | LCKTEKSRCKDRCA12 | |
| SCHEMBL30569263 | 0.79 | MAP4K4 (0.42) | LCKSRCFLT3 | |
| SCHEMBL28898414 | 0.76 | RIPK2 (0.52) | LCKTEKSRCKDRRIPK2 | |
| SCHEMBL30569254 | 0.75 | LCK (0.42) | LCKTEKSRCCA12CA1 | |
| SCHEMBL22418432 | 0.73 | BTK (0.44) | LCKSRCRETRIPK2BTK | |
| SCHEMBL30569295 | 0.72 | RET (0.56) | LCKTEKSRCNEK7RET | |
| SCHEMBL24072613 | 0.71 | ADK (0.43) | SRCRET | |
| SCHEMBL23966790 | 0.70 | RET (0.54) | LCKTEKSRCNEK7RET | |
| SCHEMBL30180780 | 0.70 | RET (0.54) | LCKTEKSRCNEK7RET | |
| SCHEMBL18045177 | 0.70 | ADK (0.44) | SRCRETFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683629-A | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2021-11-23 | — | — | CN | disclosed |