Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.54 |
| ▸ | LCK | P06239 | 3/20 | 0.54 |
| ▸ | TEK | Q02763 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 5/20 | 0.39 |
| ▸ | ADK | P55263 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675253 | 0.85 | LCK (0.39) | SRCLCKTEKCA12CA1 | |
| SCHEMBL30569254 | 0.82 | LCK (0.42) | SRCLCKTEKCA12CA1 | |
| SCHEMBL28898414 | 0.79 | RIPK2 (0.52) | SRCLCKTEKBTKFLT3 | |
| SCHEMBL28671849 | 0.75 | FLT3 (0.45) | SRCLCKTEKADKFLT3 | |
| SCHEMBL22418477 | 0.72 | TEK (0.52) | SRCLCKTEKFLT3KDR | |
| SCHEMBL20351656 | 0.72 | SRC (0.44) | SRCLCKTEKCA12CA1 | |
| SCHEMBL20351791 | 0.71 | FLT3 (0.46) | SRCLCKTEKCA12CA1 | |
| SCHEMBL7006747 | 0.70 | SRC (1.00) | SRCLCKTEKBTKKDR | |
| SCHEMBL2075215 | 0.70 | TEK (0.83) | SRCLCKTEKBTKKDR | |
| SCHEMBL22418432 | 0.70 | BTK (0.44) | SRCLCKBTKADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683629-B | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-113683629-A | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2021-11-23 | — | — | CN | disclosed |