Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 7/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756490 | 0.82 | CYP3A4 (0.40) | CYP3A4ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL4557570 | 0.79 | CYP3A4 (0.59) | CYP3A4ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9644567 | 0.79 | CYP3A4 (0.59) | CYP3A4ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL2931707 | 0.78 | CA1 (0.38) | CYP3A4ALDH1A1CES2CES1GRIN2D | |
| SCHEMBL9774781 | 0.77 | CYP3A4 (0.40) | CYP3A4ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11876093 | 0.77 | GRIN2D (0.34) | CYP3A4ALDH1A1HSD17B10KDM1AKDM1B | |
| SCHEMBL17219203 | 0.76 | CA1 (0.36) | CYP3A4ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL27850940 | 0.76 | POLB (0.32) | — | |
| SCHEMBL1042005 | 0.73 | KDM1A (0.32) | ALDH1A1KDM1AKDM1BCES2CES1 | |
| SCHEMBL11036565 | 0.72 | CYP3A4 (0.43) | CYP3A4ALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944494-A | Stabilization of trichlorodifluoro benzenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-03-16 | — | — | US | claimed |
| US-7943257-B2 | Electrolyte solvent and rechargeable lithium battery | SAMSUNG SDI CO., LTD. (KR) | 2011-05-17 | — | — | US | disclosed |
| US-20100104949-A1 | Electrolyte and rechargeable lithium battery | YAMAGUCHI TAKITARO | 2010-04-29 | — | — | US | disclosed |
| US-7595426-B2 | Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-29 | — | — | US | disclosed |
| US-20080214878-A1 | Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | US | disclosed |
| EP-1874715-A1 | METHOD FOR THE PRODUCTION OF 1,3,5-TRIFLUORO-2,4,6-TRICHLOROBENZENE FROM FLUOROBENZENE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111583-A1 | METHOD FOR THE PRODUCTION OF 1,3,5-TRIFLUORO-2,4,6-TRICHLOROBENZENE FROM FLUOROBENZENE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-26 | — | — | WO | disclosed |
| EP-0136683-B1 | FLUOROCHLOROHYDROCARBON COMPOSITIONS | DAIKIN INDUSTRIES, LTD. (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-5041674-A | Chlorinating 1-chloro-3,5-difluorobenzene, nitrating and reducing | DOWELANCO (US) | 1991-08-20 | — | — | US | disclosed |
| US-4009576-A | Regenerator for rotary Rankine cycle engines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
| US-3950950-A | Rotary Rankine engine powered electric generating apparatus | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-04-20 | — | — | US | disclosed |
| US-3944494-A | Stabilization of trichlorodifluoro benzenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
| US-3944494-A | Stabilization of trichlorodifluoro benzenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214878-A1 | Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives | FLNB, AFF1, AFF2 | CYP3A4 109/4885ALDH1A1 1093/4885HPGD 1547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.