Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 6/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358268 | 0.83 | CYP3A4 (0.41) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 | |
| SCHEMBL1756502 | 0.79 | CYP3A4 (0.47) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 | |
| SCHEMBL9774781 | 0.79 | CYP3A4 (0.40) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 | |
| SCHEMBL11876093 | 0.79 | GRIN2D (0.34) | CYP3A4HSD17B10ALDH1A1KDM1AKDM1B | |
| Pentachlorobenzene SCHEMBL183144 | 0.75 | CYP3A4 (1.00) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 | |
| Pentachlorobenzene SCHEMBL11455164 | 0.75 | CYP3A4 (1.00) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 | |
| SCHEMBL10982689 | 0.75 | CYP3A4 (0.36) | CYP3A4HPGDHSD17B10TSHRALDH1A1 | |
| SCHEMBL11716199 | 0.75 | HSD17B10 (0.65) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 | |
| SCHEMBL28675338 | 0.75 | CYP3A4 (0.43) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 | |
| SCHEMBL10898146 | 0.75 | HSD17B10 (0.59) | CYP3A4HPGDHSD17B10TSHRHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611717-B | Preparation method of polyfluorobenzaldehyde | 上海万溯药业有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-115611717-B | Preparation method of polyfluorobenzaldehyde | 上海万溯药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-7595426-B2 | Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-29 | — | — | US | disclosed |
| US-20080214878-A1 | Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | US | disclosed |
| EP-1874715-A1 | METHOD FOR THE PRODUCTION OF 1,3,5-TRIFLUORO-2,4,6-TRICHLOROBENZENE FROM FLUOROBENZENE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111583-A1 | METHOD FOR THE PRODUCTION OF 1,3,5-TRIFLUORO-2,4,6-TRICHLOROBENZENE FROM FLUOROBENZENE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-26 | — | — | WO | disclosed |
| EP-0270965-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3,5-DICHLORO-2,4-DIFLUOROBENZENES | BAYER AG (DE) | 1992-09-02 | — | — | EP | disclosed |
| EP-0270964-B1 | PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES | BAYER AG (DE) | 1992-07-08 | — | — | EP | disclosed |
| EP-0270970-B1 | PROCESS FOR PREPARING 3,5 DICHLORO-2,4 DIFLUORONITROBENZENE | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-5081288-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3,5-DICHLORO-2,4-DIFLUORO-BENZENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |
| US-4868347-A | SOLVENT EXTRACTION | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
| EP-0270970-A2 | Process for preparing 3,5 dichloro-2,4 difluoronitrobenzene | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| EP-0270965-A2 | Process for the preparation of substituted 3,5-dichloro-2,4-difluorobenzenes | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| EP-0270964-A2 | Process for obtaining substituted fluorobenzenes | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214878-A1 | Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives | FLNB, AFF1, AFF2 | CYP3A4 109/4885HPGD 1547/4885HSD17B10 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.