SCHEMBL28675718

SCHEMBL28675718

COc1cc(C=O)c(Cc2ccccc2)c(OC)c1O

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 17/20 0.50
TLR2 O60603 1/20 0.45
TLR1 Q15399 1/20 0.45
TLR6 Q9Y2C9 1/20 0.45
ALOX5 P09917 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27871308 0.81 ALOX5 (0.48) ERN1ALOX5MAPT
SCHEMBL2875694 0.80 ALDH1A1 (0.50) ERN1TLR2TLR1TLR6MAPT
SCHEMBL7948327 0.78 CA1 (0.53) ERN1TLR2TLR1TLR6MAPT
SCHEMBL17821776 0.78 ERN1 (0.53) ERN1TLR2TLR1TLR6MAPT
SCHEMBL29014399 0.77 ALOX5 (0.54) ERN1ALOX5LMNAMAPT
SCHEMBL16093499 0.75 ERN1 (0.62) ERN1TLR2TLR1TLR6LMNA
SCHEMBL16385983 0.75 ERN1 (0.67) ERN1TLR2TLR1TLR6LMNA
SCHEMBL21933489 0.74 ERN1 (0.54) ERN1TLR2TLR1TLR6LMNA
SCHEMBL25884390 0.74 ERN1 (0.61) ERN1LMNAMAPT
SCHEMBL6536167 0.73 ERN1 (0.53) ERN1TLR2TLR1TLR6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113637000-B Compound with plant growth regulating activity and preparation method thereof 鹤壁全丰生物科技有限公司 2023-11-21 CN claimed
CN-113637000-A Compound with plant growth regulation activity and preparation method thereof 鹤壁全丰生物科技有限公司 2021-11-12 CN claimed
CN-113637000-B Compound with plant growth regulating activity and preparation method thereof 鹤壁全丰生物科技有限公司 2023-11-21 CN disclosed
CN-113637000-A Compound with plant growth regulation activity and preparation method thereof 鹤壁全丰生物科技有限公司 2021-11-12 CN disclosed