Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 5/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873591 | 0.85 | CA1 (0.40) | CA1CA2TYRLTA4HSHBG | |
| SCHEMBL28275335 | 0.85 | CA1 (0.45) | CA1CA2KDM4EGAAMAPT | |
| SCHEMBL2875694 | 0.83 | ALDH1A1 (0.50) | ERN1LTA4HTLR2TLR1TLR6 | |
| SCHEMBL28512054 | 0.83 | PTPN1 (0.41) | CA1CA2MAPT | |
| Bicarbonate SCHEMBL28192811 | 0.82 | CA1 (0.38) | CA1CA2PLA2G2A | |
| SCHEMBL1396832 | 0.81 | CA1 (0.54) | CA1CA2ERN1TRIM24TRIM33 | |
| SCHEMBL20455996 | 0.80 | CA1 (0.50) | CA1CA2ERN1TRIM24TRIM33 | |
| SCHEMBL20506784 | 0.79 | CA1 (0.54) | CA1CA2ERN1TRIM24TRIM33 | |
| SCHEMBL28909126 | 0.79 | ERN1 (0.46) | ERN1TRIM24TRIM33MCL1KDM4E | |
| SCHEMBL7948311 | 0.79 | HNF4A (0.50) | HTTALDH1A1MAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015121379-A2 | METHODS OF IMPROVING PRODUCTION OF VANILLIN | EVOLVA SA (CH) | 2015-08-20 | — | — | WO | claimed |
| CN-107881188-A | A kind of method that whole-cell catalyst prepares aromatic aldehyde and/or aromatic alcohol | 上海交通大学 | 2018-04-06 | — | — | CN | disclosed |
| CN-107266297-A | Prenylation hydroxy diphenyl ethylene, the pharmaceutical composition comprising it, purposes and preparation method thereof | 悉尼大学 | 2017-10-20 | — | — | CN | disclosed |
| US-20160367685-A1 | DUPA-INDENOISOQUINOLINE CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-12-22 | — | — | US | disclosed |
| CN-105899234-A | Dupa-indenoisoquinoline conjugates | 普度研究基金会 | 2016-08-24 | — | — | CN | disclosed |
| WO-2015069766-A1 | DUPA-INDENOISOQUINOLINE CONJUGATES | PURDUE RESEARCH FOUNDATION (US) | 2015-05-14 | — | — | WO | disclosed |
| US-6261814-B1 | MIXING PURIFIED, BIOLOGICALLY-DERIVED REDUCTASE FROM NOCARDIA SPECIES WITH CARBOXYLIC ACID OR DERIVATIVE; PRODUCTION OF VANILLIN FROM VANILLIC ACID | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2001-07-17 | — | — | US | disclosed |
| WO-1998040472-A2 | CARBOXYLIC ACID REDUCTASE, AND METHODS OF USING SAME | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-09-17 | — | — | WO | disclosed |
| US-5795759-A | Carboxylic acid reductase, and methods of using same | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160367685-A1 | DUPA-INDENOISOQUINOLINE CONJUGATES | PDS5B, KLK3, PDS5A | CA1 4807/4885CA2 4742/4885ERN1 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.