SCHEMBL28675796

SCHEMBL28675796

Cc1c(C)c2c(c(Br)c1F)Cc1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP3K9 P80192 1/20 0.36
MAP3K11 Q16584 1/20 0.36
PGR P06401 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
PNMT P11086 1/20 0.33
MAOA P21397 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
ACHE P22303 1/20 0.31
BCHE P06276 1/20 0.31
CES1 P23141 1/20 0.31
ALDH1A1 P00352 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28945156 0.81 MAP3K9 (0.38) MAP3K9MAP3K11PGRCA1CA2
SCHEMBL18774731 0.74 MAP3K9 (0.46) MAP3K9MAP3K11PGRCA1CA2
SCHEMBL8622497 0.73 MAP3K9 (0.42) MAP3K9MAP3K11PGRCA1CA2
SCHEMBL4817874 0.71 MAP3K9 (0.38) MAP3K9MAP3K11PGRCA1CA2
SCHEMBL20502811 0.70 PGR (0.38) MAP3K9MAP3K11PGRCA1CA2
SCHEMBL28680784 0.70 KDR (0.38) MAP3K9MAP3K11CA1CA2CA4
SCHEMBL21925182 0.69 ACHE (0.41) MAP3K9MAP3K11PGRCA1CA2
SCHEMBL20382173 0.69 MAP3K9 (0.36) MAP3K9MAP3K11PGRCA1CA2
SCHEMBL16275938 0.68 MAP3K9 (0.38) MAP3K9MAP3K11PGRCA1CA2
SCHEMBL22067694 0.68 MAP3K9 (0.55) MAP3K9MAP3K11PGRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113841262-A Organic light emitting device 株式会社LG化学 2021-12-24 CN disclosed