SCHEMBL28675804

SCHEMBL28675804

Cc1ccc2c(c1)C=CC2(C)[Zr](C)C

nearest known ligand 0.31

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16242531 0.78 THRB (0.34) THRBTDP1TP53CYP3A4ALOX15
SCHEMBL22616905 0.74 THRB (0.32) THRBTDP1TP53CYP3A4ALOX15
SCHEMBL28666658 0.74 THRB (0.32) THRBTDP1TP53CYP3A4ALOX15
SCHEMBL28416382 0.74 OXTR (0.33) MAPT
Hydrochloric Acid SCHEMBL28662631 0.73 THRB (0.31) THRBTDP1TP53CYP3A4ALOX15
SCHEMBL22616638 0.67 MEN1 (0.33) THRBTDP1MEN1LMNAMAPT
SCHEMBL7907689 0.67
SCHEMBL31686125 0.67 IDO1 (0.35) THRBTDP1TP53CYP3A4ALOX15
Hydrochloric Acid SCHEMBL28662106 0.66 MEN1 (0.32) THRBTDP1MEN1LMNAMAPT
SCHEMBL25329185 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116635430-A Thermoplastic compositions comprising bimodal polyethylene and articles made therefrom 陶氏环球技术有限责任公司 2023-08-22 CN disclosed
CN-115884993-A Bimodal polyethylene copolymers and films thereof 陶氏环球技术有限责任公司 2023-03-31 CN disclosed
CN-115803351-A Attenuated mixed catalysts 陶氏环球技术有限责任公司 2023-03-14 CN disclosed
CN-115698105-A Chemical conversion catalyst 陶氏环球技术有限责任公司 2023-02-03 CN disclosed
CN-115698102-A Attenuated post metallocene catalysts 陶氏环球技术有限责任公司 2023-02-03 CN disclosed
CN-115698101-A Attenuated post metallocene catalysts 陶氏环球技术有限责任公司 2023-02-03 CN disclosed
CN-115515991-A Attenuated post metallocene catalyst 陶氏环球技术有限责任公司 2022-12-23 CN disclosed
CN-114096548-A Process for preparing metal ligand complexes 陶氏环球技术有限责任公司 2022-02-25 CN disclosed
CN-113748140-A Metal-ligand complexes 陶氏环球技术有限责任公司 2021-12-03 CN disclosed