SCHEMBL22616638

SCHEMBL22616638

[Li]C1(CC)C=Cc2cc(C)ccc21

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22616905 0.76 THRB (0.32) MEN1LMNAMAPTTHRBHTT
SCHEMBL17008829 0.76 KDM4E (0.34)
Hydrochloric Acid SCHEMBL28662106 0.74 MEN1 (0.32) MEN1LMNAMAPTTHRBHTT
SCHEMBL16242531 0.71 THRB (0.34) MEN1LMNAMAPTTHRBHTT
SCHEMBL28666658 0.68 THRB (0.32) MEN1LMNAMAPTTHRBHTT
SCHEMBL7907689 0.68
Hydrochloric Acid SCHEMBL28662631 0.67 THRB (0.31) MEN1LMNAMAPTTHRBHTT
SCHEMBL28675804 0.67 THRB (0.31) MEN1LMNAMAPTTHRBHTT
SCHEMBL22616620 0.64
SCHEMBL28676393 0.64 SIGMAR1 (0.36) MEN1LMNAMAPTTHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441748-B2 Metal-ligand complexes DOW GLOBAL TECHNOLOGIES LLC (US) 2025-10-14 US disclosed
CN-113748140-B Metal-ligand complexes 陶氏环球技术有限责任公司 2025-03-11 CN disclosed
US-20220259231-A1 METAL-LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2022-08-18 US disclosed
EP-3962970-A1 METAL-LIGAND COMPLEXES Dow Global Technologies LLC (US) 2022-03-09 EP disclosed
CN-113748140-A Metal-ligand complexes 陶氏环球技术有限责任公司 2021-12-03 CN disclosed
WO-2020223142-A1 METAL-LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2020-11-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259231-A1 METAL-LIGAND COMPLEXES ARL1, CRKL, SAAL1 MEN1 1113/4885LMNA 2908/4885MAPT 4710/4885
US-12441748-B2 Metal-ligand complexes ARL1, CRKL, SAAL1 MEN1 1113/4885LMNA 2908/4885MAPT 4710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.