SCHEMBL28675865

SCHEMBL28675865

CC(C)c1ccc2[nH]c3cc4ccccc4cc3c2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.62
KDM4E B2RXH2 5/20 0.44
HSD17B10 Q99714 3/20 0.44
LMNA P02545 1/20 0.44
AHR P35869 1/20 0.42
GAA P10253 1/20 0.42
UGT2B7 P16662 1/20 0.42
MAPT P10636 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 1/20 0.41
VDR P11473 1/20 0.41
TSHR P16473 1/20 0.39
GFER P55789 1/20 0.39
HTR1D P28221 1/20 0.39
CNR1 P21554 1/20 0.39
PTGS2 P35354 2/20 0.38
ABCC4 O15439 1/20 0.38
C5 P01031 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21376875 0.85 KIF11 (0.62) KIF11KDM4EHSD17B10LMNAGAA
SCHEMBL13010630 0.84 KIF11 (0.79) KIF11KDM4EHSD17B10AHRGAA
SCHEMBL31549973 0.84 KIF11 (0.79) KIF11KDM4EHSD17B10AHRGAA
SCHEMBL28256205 0.81 KIF11 (0.56) KIF11KDM4EGAA
SCHEMBL10743051 0.79 AHR (0.56) KIF11KDM4EHSD17B10LMNAAHR
SCHEMBL29385786 0.79 AHR (0.56) KIF11KDM4EHSD17B10LMNAAHR
SCHEMBL10130992 0.77 KIF11 (0.51) KIF11KDM4EGAAALDH1A1VDR
SCHEMBL19731074 0.77 AHR (0.61) KIF11KDM4EHSD17B10LMNAAHR
SCHEMBL12219479 0.77 AHR (0.61) KIF11KDM4EHSD17B10LMNAAHR
SCHEMBL12219473 0.77 AHR (0.61) KIF11KDM4EHSD17B10LMNAAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113582907-A Preparation method of 5-hydrogen-benzo [ B ] carbazole derivative and derivative thereof 陕西维世诺新材料有限公司 2021-11-02 CN disclosed